Jan 15, 2026 2 min read 0 views

Structure Therapeutics Stock Surges on Positive Obesity Pill Data

Structure Therapeutics shares have risen over 130% in three months after reporting positive clinical trial results for its oral obesity pill, with analysts maintaining bullish ratings.

Structure Therapeutics Stock Surges on Positive Obesity Pill Data

Shares of Structure Therapeutics Inc. (NASDAQ:GPCR) have climbed more than 130% over the past three months. A significant portion of this gain occurred since early December, following the release of positive data from a study of its oral obesity pill.

A clinical trial tested aleniglipron on obese or overweight patients who also had one or more weight-related co-morbidities. After 36 weeks of treatment at a 120 mg dose, participants demonstrated an average weight loss of 11.3%. The development is notable as the current obesity treatment market is largely dominated by injectable drugs.

The company also reported ongoing research involving a 240 mg dose. This higher dosage yielded a 15.3% average weight loss at the 36-week mark.

On December 17, Structure Therapeutics announced it had initiated the first human trial for ACCG-2671. This is an oral small-molecule amylin receptor agonist also being developed to treat obesity.

Wall Street analysts maintain a bullish stance on the stock. As of the market close on January 12, the consensus rating is Strong Buy, with a one-year average share price target of $104. This target implies a potential upside of 49.94% from recent levels.

Recent analyst actions include LifeSci Capital reiterating a Buy rating on January 6, with a price target of $107. This followed a January 2 update from BMO Capital, which maintained its Outperform rating and set a price target of $130.

Structure Therapeutics Inc. is a biotechnology company focused on developing treatments for chronic metabolic conditions.

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